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High dose oral supplementation is an effective alternative to parenteral treatment Randomized studies of daily high oral doses of 1,0002,000 g have shown equivalence or superiority to injected B 12
It is formulated to support normal energy production, metabolism and the proper functioning of the nervous system
arguments against the use of oral cobalamin Oral treatment may be considered in certain situationsfor example, in mild or subclinical deficiency with no clinical features and when absorption and compliance are definitely not a problem
Metformin may result in suboptimal oral vitamin B12 absorption by competitively blocking the calcium-dependent binding of the intrinsic factor-vitamin B12 complex to its receptor
It has been found that research has mostly been conducted on the animals and little evidence has been found on the canine itself, thus it should never be used in place of professional veterinary care
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